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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K5
All Species:
26.97
Human Site:
T1252
Identified Species:
59.33
UniProt:
Q99683
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99683
NP_005914.1
1374
154537
T1252
L
G
R
M
K
I
E
T
N
R
L
L
E
E
L
Chimpanzee
Pan troglodytes
XP_001171211
1375
154924
T1253
L
G
R
M
K
I
E
T
N
R
L
L
E
E
L
Rhesus Macaque
Macaca mulatta
XP_001111127
1297
143635
L1185
T
D
R
L
R
E
V
L
A
E
K
E
R
E
Y
Dog
Lupus familis
XP_533420
1645
181128
T1523
L
G
R
M
K
I
E
T
N
R
L
L
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
O35099
1380
154441
T1259
L
G
R
M
K
I
E
T
N
R
L
L
E
E
L
Rat
Rattus norvegicus
XP_001073260
1338
150427
T1216
L
G
R
M
K
M
E
T
N
R
L
L
E
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511920
1243
141469
L1139
E
R
E
F
Q
A
L
L
H
Q
A
I
E
E
K
Chicken
Gallus gallus
XP_419725
1260
143069
T1138
L
G
R
L
K
L
E
T
N
R
L
L
E
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155222
1364
153160
T1243
L
G
R
M
K
L
E
T
K
R
L
L
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477089
1363
155478
R1162
D
N
Q
Q
K
L
Q
R
Q
L
L
E
Q
Q
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202919
1288
145042
Q1164
H
Q
R
L
V
Q
E
Q
G
R
L
L
Q
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
44.9
68
N.A.
94.1
92.7
N.A.
84.4
80.4
N.A.
71.7
N.A.
40.6
N.A.
N.A.
44.6
Protein Similarity:
100
99.4
61.3
73.1
N.A.
95.8
94.4
N.A.
87.8
87
N.A.
84.1
N.A.
58.2
N.A.
N.A.
60.7
P-Site Identity:
100
100
13.3
100
N.A.
100
93.3
N.A.
13.3
86.6
N.A.
86.6
N.A.
13.3
N.A.
N.A.
46.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
40
100
N.A.
93.3
N.A.
46.6
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
10
0
0
10
73
0
0
10
0
19
73
91
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
64
0
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
37
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
73
0
0
0
10
0
10
0
0
0
10
% K
% Leu:
64
0
0
28
0
28
10
19
0
10
82
73
0
0
73
% L
% Met:
0
0
0
55
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
55
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
10
10
10
10
10
10
10
10
0
0
19
10
0
% Q
% Arg:
0
10
82
0
10
0
0
10
0
73
0
0
10
0
10
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
64
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _